When it comes to cancer, it seems like everyone has a story that hits home.

For Dr. Howard Krein, chief medical officer of StartUp Health, the main element in the narrative was the frustration he felt when even all the resources in the world meant nothing.

See, Krein’s brother-in-law, Beau Biden —son of Vice President Joe Biden — began a drawn-out battle against an aggressive type of brain cancer in 2010.